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Article

Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer

5 Nov 2014

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Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 25370038
DOI: 10.1038/ejhg.2014.242

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancerPMID 25370038Read ↗

POLE mutations in colorectal cancer: a new biomarker?Semantic proximity Read ↗

Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1.Semantic proximity Read ↗

The clinical landscape of POLE-mutant colorectal cancer: a retrospective analysis of real-world outcome.Semantic proximity Read ↗

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.Semantic proximity Read ↗

POLE somatic mutations in advanced colorectal cancer.Semantic proximity Read ↗

Germline mutation p.N363K in POLE is associated with an increased risk of colorectal cancer and giant cell glioblastomaSemantic proximity Read ↗

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomasSemantic proximity Read ↗

The somatic <i>POLE</i> P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapySemantic proximity Read ↗

Distinct clinical pattern of colorectal cancer patients with POLE mutations: A retrospective study on real-world dataSemantic proximity Read ↗

Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE geneSemantic proximity Read ↗

High mutational burden in colorectal carcinomas with monoallelic POLE mutations: absence of allelic loss and gene promoter methylation.Semantic proximity Read ↗

A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine.Semantic proximity Read ↗

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