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Article

Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt).

Human genetics - 1 Jan 2015

Sikora Jacquelyn L, Logue Mark W, Chan Gloria G, Spencer Brian H, Prokaeva Tatiana B, Baldwin Clinton T, Seldin David C, Connors Lawreen H

Abstract excerpt

Wild-type transthyretin amyloidosis (ATTRwt), typically diagnosed as congestive heart failure in elderly Caucasian men, features myocardial amyloid deposits of wild-type plasma protein transthyretin (TTR). ATTRwt is sporadic, its pathogenesis is poorly understood, and currently there are no biomarkers for diagnosis or prognosis. Genetic studies of variant-associated transthyretin amyloidosis have suggested that...

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Identifiers

PMID: 25367359
DOI: 10.1007/s00439-014-1499-0
PMCID: PMC4282974

Genes

TTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt).PMID 25367359Read ↗

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