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Article

In silico analysis of TTR gene (coding and non-coding regions, and interactive network) and its implications in transthyretin-related amyloidosis.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Sept 2014

Polimanti Renato, Di Girolamo Marco, Manfellotto Dario, Fuciarelli Maria

Abstract excerpt

INTRODUCTION: Transthyretin (TTR)-related amyloidosis is a life-threatening disease. Currently, several questions about the pathogenic mechanisms of TTR-related amyloidosis remain unanswered. METHODS: We have investigated various TTR-related issues using different in silico approaches. RESULTS: Using an amino acid similarity-based analysis, we have indicated the most relevant TTR secondary structures in...

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Identifiers

PMID: 24779883
DOI: 10.3109/13506129.2014.900487

Genes

TTR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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