Article
A genome-wide association study for diabetic retinopathy in a Japanese population: potential association with a long intergenic non-coding RNA.
PloS one - 1 Jan 2014
Awata Takuya, Yamashita Hisakuni, Kurihara Susumu, Morita-Ohkubo Tomoko, Miyashita Yumi, Katayama Shigehiro, Mori Keisuke, Yoneya Shin, Kohda Masakazu, Okazaki Yasushi, Maruyama Taro, Shimada Akira, Yasuda Kazuki, Nishida Nao, Tokunaga Katsushi, Koike Asako
Abstract excerpt
Elucidation of the genetic susceptibility factors for diabetic retinopathy (DR) is important to gain insight into the pathogenesis of DR, and may help to define genetic risk factors for this condition. In the present study, we conducted a three-stage genome-wide association study (GWAS) to identify DR susceptibility loci in Japanese patients, which comprised a total of 837 type 2 diabetes patients with DR (cases)...
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