Article
From molecular signatures to predictive biomarkers: modeling disease pathophysiology and drug mechanism of action
22 Aug 2014
Abstract excerpt
Omics profiling significantly expanded the molecular landscape describing clinical phenotypes. Association analysis resulted in first diagnostic and prognostic biomarker signatures entering clinical utility. However, utilizing Omics for deepening our understanding of disease pathophysiology, and further including specific interference with drug mechanism of action on a molecular process level still sees limited...
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