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Article

Genotoxic effects of two-generational selenium deficiency in mouse somatic and testicular cells.

Mutagenesis - 1 Mar 2015

Graupner Anne, Instanes Christine, Andersen Jill M, Brandt-Kjelsen Anicke, Dertinger Stephen D, Salbu Brit, Brunborg Gunnar, Olsen Ann-Karin

Abstract excerpt

Many studies have investigated genotoxic effects of high Se diets but very few have addressed the genotoxicity of Se deprivation and its consequences in germ cells and none in somatic cells. To address these data gaps, C57BL/6 male mice were subjected to Se deprivation starting in the parental generation, i.e. before conception. Mice were given a diet of either low (0.01mg Se/kg diet) or normal (0.23mg Se/kg...

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Identifiers

PMID: 25358475
DOI: 10.1093/mutage/geu059
PMCID: PMC4329509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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