Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Breast cancer risk associated with CHEK2 mutations.

Oncology nursing forum - 1 Nov 2014

Mahon Suzanne M

Abstract excerpt

Most efforts to identify individuals who have a hereditary predisposition for developing breast cancer had focused on the BRCA1 and BRCA2 genes. Less common susceptibility genes also are associated with increased risk for developing breast cancer, but until recently have often gone undetected. With the advent of next generation sequencing (NGS), many families with suspected hereditary risk are undergoing testing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Checkpoint Kinase 2
Share to BRCA1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 gene

Share to CHEK2 gene

Share to Mutation

Share to Risk Factors

Source

Identifiers

PMID: 25355026
DOI: 10.1188/14.ONF.692-694

Genes

CHEK2
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Breast cancer risk associated with CHEK2 mutations.PMID 25355026Read ↗

Management of individuals with germline pathogenic/likely pathogenic variants in CHEK2: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG).Semantic proximity Read ↗

CHEK2-related breast cancer: real-world challenges.Semantic proximity Read ↗

Is CHEK2 a moderate-risk breast cancer gene or the younger sister of Li-Fraumeni?Semantic proximity Read ↗

A CHEK2 Genetic Variant Contributing to a Substantial Fraction of Familial Breast CancerSemantic proximity Read ↗

High risk of breast cancer in women with biallelic pathogenic variants in CHEK2.Semantic proximity Read ↗

Skin cancer risk in CHEK2 mutation carriers.Semantic proximity Read ↗

Breast cancer risk is similar for CHEK2 founder and non-founder mutation carriers.Semantic proximity Read ↗

CHEK2 Germline Variants and Their Clinical Implications: Experience from a Turkish Hereditary Cancer Cohort.Semantic proximity Read ↗

Germline variant profiling of CHEK2 sequencing variants in breast cancer patients.Semantic proximity Read ↗

Comprehensive analysis and ACMG-based classification of CHEK2 variants in hereditary cancer patients.Semantic proximity Read ↗

Differences in cancer prevalence among CHEK2 carriers identified via multi-gene panel testing.Semantic proximity Read ↗

Concurrent Pathogenic Variants of BRCA1, MUTYH and CHEK2 in a Hereditary Cancer Family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.