Article
Smoking attenuated the association between IκBα rs696 polymorphism and defective spermatogenesis in humans.
Andrologia - 1 Nov 2015
Yu B, Ding Q, Zheng T, Jiang L, Li Q, Sun X, Bai C, Huang Z
Abstract excerpt
Defective spermatogenesis is prevalent in infertile men, but the molecular mechanisms underlying its aetiology are largely unknown. In this study, a proposed association between IκBα SNPs, smoking-related ROS and sperm quality was investigated. Two polymorphisms in the IκBα gene, rs2233406 and rs696 were genotyped in 342 controls and 338 patients with defective spermatogenesis from a southern Chinese population....
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