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Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of A lzheimer's Disease

29 Oct 2014

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disorder and the leading cause of age-related dementia worldwide. Several models for AD have been developed to provide information regarding the initial changes that lead to degeneration. Transgenic mouse models recapitulate many, but not all, of the features of AD, most likely because of the high complexity of the pathology. In this context, the...

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PMID: 25351914
DOI: 10.1111/bpa.12226

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