Article
Telomerase gene mutations and telomere length shortening in patients with idiopathic pulmonary fibrosis in a Chinese population.
Respirology (Carlton, Vic.) - 1 Jan 2015
Dai Jinghong, Cai Hourong, Zhuang Yi, Wu Yongzheng, Min Haiyan, Li Jinheng, Shi Yi, Gao Qian, Yi Long
Abstract excerpt
BACKGROUND AND OBJECTIVE: Idiopathic pulmonary fibrosis (IPF) is an age-related disease and the most common manifestation of telomere-mediated disorders. METHODS: We collected detailed medical histories and DNA samples from 100 IPF patients seen at Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University. All patients had sporadic IPF, with no family history reported. We screened all...
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