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Differential antiviral immunity to Japanese encephalitis virus in developing cortical organoids

18 Jun 2018

Abstract excerpt

Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) poses a serious threat to the world's public health yet without a cure. Certain JEV-infected neural cells express a subset of previously identified intrinsic antiviral interferon stimulated genes (ISGs), indicating brain cells retain autonomous antiviral immunity. However, whether this happens in composited brain remains unclear. Human...

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PMID: 29915260
DOI: 10.1038/s41419-018-0763-y

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