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Article

Current Perspectives on HIV-1 Antiretroviral Drug Resistance

24 Oct 2014

Abstract excerpt

Current advancements in antiretroviral therapy (ART) have turned HIV-1 infection into a chronic and manageable disease. However, treatment is only effective until HIV-1 develops resistance against the administered drugs. The most recent antiretroviral drugs have become superior at delaying the evolution of acquired drug resistance. In this review, the viral fitness and its correlation to HIV-1 mutation rates and...

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Identifiers

PMID: 25341668
DOI: 10.3390/v6104095

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