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Article

In vitro and in vivo models of Staphylococcus aureus endophthalmitis implicate specific nutrients in ocular infection.

PloS one - 1 Jan 2014

Sadaka Ama, Palmer Kelli, Suzuki Takashi, Gilmore Michael S

Abstract excerpt

PURPOSE: To define global transcriptional responses of Staphylococcus aureus and its codY mutant (CodY is a transcription regulator of virulence and metabolic genes in response to branched-chain amino acids) when growing in bovine aqueous (AH) and vitreous humor (VH) in vitro, and to investigate the impact of codY deletion on S. aureus virulence in a novel murine anterior chamber (AC) infection model. METHODS:...

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Identifiers

PMID: 25340474
DOI: 10.1371/journal.pone.0110872
PMCID: PMC4207797

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In vitro and in vivo models of Staphylococcus aureus endophthalmitis implicate specific nutrients in ocular infection.PMID 25340474Read ↗

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