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Mechanisms of immune regulation by IVIG

9 Oct 2014

Abstract excerpt

PURPOSE OF REVIEW: In the past few years there have been many advances in our understanding of the mechanisms by which intravenous immune globulin (IVIG) modulates immune function in autoimmune disorders. RECENT FINDINGS: Previous investigations have focused on the Fc domain of the IgG molecule, and the role of the FcγRIIB receptor and the sialylated Fc domain that have been show to mediate the anti-inflammatory...

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PMID: 25337683
DOI: 10.1097/aci.0000000000000116

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