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Article

Angioimmunoblastic T-cell lymphoma in Taiwan shows a frequent gain of ITK gene.

International journal of clinical and experimental pathology - 1 Jan 2014

Liang Peir-In, Chang Sheng-Tsung, Lin Ming-Yen, Hsieh Yen-Chuan, Chu Pei-Yi, Chen Chih-Jung, Lin Kai-Jen, Jung Yun-Chih, Hwang Wei-Shou, Huang Wen-Tsung, Chang Wei-Chin, Ye Hongtao, Chuang Shih-Sung

Abstract excerpt

Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive peripheral T-cell lymphoma (PTCL) of follicular helper T-cell origin and is rare in Taiwan. There are overlapping features of AITL and peripheral T-cell lymphoma with a follicular growth pattern (PTCL-F). Around one fifth of PTCL-F exhibits t(5;9)(q33;q22)/ITK-SYK chromosomal translocation, which is essentially absent in AITL. We retrospectively...

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Share to Chromosomes, Human, Pair 5
Share to Chromosomes, Human, Pair 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Amplification

Share to Herpesvirus 4, Human

Share to Lymphoma, T-Cell

Share to Syk Kinase

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Share to Translocation, Genetic

Source

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Identifiers

PMID: 25337257
PMCID: PMC4203228

Genes

ITK
SYK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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