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Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases

26 Apr 2011

Abstract excerpt

INTRODUCTION: The objective of this study is to determine if multiple systemic autoimmune diseases (SAID) share gene expression pathways that could provide insights into pathogenic mechanisms common to these disorders. METHODS: RNA microarray analyses (Agilent Human 1A(V2) 20K oligo arrays) were used to quantify gene expression in peripheral blood cells from 20 monozygotic (MZ) twin pairs discordant for SAID. Six...

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Inflammatory Myopathies and Dermatomyositis
Rheumatoid Arthritis Research and Therapies
Systemic Lupus Erythematosus Research

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PMID: 21521520
DOI: 10.1186/ar3330

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