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Article

Prevalence of Myocilin Mutations in a Cohort of Patients with Juvenile Open-Angle Glaucoma from sub-Saharan Africa.

Ophthalmology. Glaucoma - 1 Jan 2025

Olawoye Olusola, Young Brian P, Nyunt Angela W, Fafowora Oluwatoyin F, Ajani Magdalene, Sarimiye Tarela, Creemer Brendan A, Roos Ben R, Coleman Anne L, Gorin Michael B, Hauser Michael A, Scheetz Todd E, Ashaye Adeyinka, Fingert John H

Abstract excerpt

PURPOSE: Determine the prevalence and the role of myocilin (MYOC) gene mutations in a sub-Saharan population of patients with juvenile open-angle glaucoma (JOAG). DESIGN: Prospective case-control. PARTICIPANTS: Forty-five patients with JOAG and 41 normal control subjects from the ophthalmology clinics of the University College Hospital Ibadan, Nigeria. METHODS: DNA was tested for MYOC coding sequence mutations...

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Identifiers

PMID: 40280414
DOI: 10.1016/j.ogla.2025.04.010
PMCID: PMC12459295

Genes

MYOC

Variants

Provenance

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