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Article

Higher prevalence of myocilin mutations in advanced glaucoma in comparison with less advanced disease in an Australasian disease registry.

Ophthalmology - 1 Jun 2013

Souzeau Emmanuelle, Burdon Kathryn P, Dubowsky Andrew, Grist Scott, Usher Bronwyn, Fitzgerald Jude T, Crawford April, Hewitt Alex W, Goldberg Ivan, Mills Richard A, Ruddle Jonathan B, Landers John, Mackey David A, Craig Jamie E

Abstract excerpt

OBJECTIVES: To determine the proportion of all Myocilin coding mutations responsible for advanced primary open-angle glaucoma (POAG) in early-age-at-onset individuals and to investigate the prevalence of exon 3 Myocilin mutations in advanced POAG at any age at onset in a large Australasian cohort. DESIGN: Cross-sectional study using a national disease registry. PARTICIPANTS: One thousand sixty individuals with...

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PMID: 23453510
DOI: 10.1016/j.ophtha.2012.11.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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