Article
Integrative Analysis of FOXP1 Function Reveals a Tumor-Suppressive Effect in Prostate Cancer
20 Oct 2014
Abstract excerpt
The transcriptional network of the androgen receptor (AR), a key molecule of prostate cancer, is frequently modulated by interactions with other transcriptional factors such as forkhead box protein A1 (FOXA1). However, global regulatory mechanisms of AR signaling mediated by such factors have not been well investigated. Here we conducted a chromatin immunoprecipitation sequence analysis, which revealed that...
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