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Article

Genetic association and gene expression studies suggest that genetic variants in the SYNE1 and TNF genes are related to menstrual migraine.

The journal of headache and pain - 14 Oct 2014

Rodriguez-Acevedo Astrid J, Smith Robert A, Roy Bishakha, Sutherland Heidi, Lea Rod A, Frith Alison, MacGregor E Anne, Griffiths Lyn R

Abstract excerpt

BACKGROUND: Menstrual migraine (MM) encompasses pure menstrual migraine (PMM) and menstrually-related migraine (MRM). This study was aimed at investigating genetic variants that are potentially related to MM, specifically undertaking genotyping and mRNA expression analysis of the ESR1, PGR, SYNE1 and TNF genes in MM cases and non-migraine controls. METHODS: A total of 37 variants distributed across 14 genes were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25315199
DOI: 10.1186/1129-2377-15-62
PMCID: PMC4196204

Genes

TNF
ESR1
PGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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