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Article

The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups.

Neurogenetics - 1 Jun 2004

Colson Natalie J, Lea Rod A, Quinlan Sharon, MacMillan John, Griffiths Lyn R

Abstract excerpt

Migraine is a painful and debilitating disorder with a significant genetic component. Steroid hormones, in particular estrogen, have long been considered to play a role in migraine, as variations in hormone levels are associated with migraine onset in many sufferers of the disorder. Steroid hormones mediate their activity via hormone receptors, which have a wide tissue distribution. Estrogen receptors have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15133719
DOI: 10.1007/s10048-004-0181-4

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups.PMID 15133719Read ↗

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Association of ESR1 Polymorphisms with Susceptibility to Migraine: A Meta-Analysis and Trial Sequential Analysis.Semantic proximity Read ↗

Contribution of polymorphisms in ESR1, ESR2, FSHR, CYP19A1, SHBG, and NRIP1 genes to migraine susceptibility in Turkish population.Semantic proximity Read ↗

Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene.Semantic proximity Read ↗

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Multilocus analyses reveal involvement of the ESR1, ESR2, and FSHR genes in migraine.Semantic proximity Read ↗

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