Article
Survival, proliferation and differentiation enhancement of neural stem cells cultured in three-dimensional polyethylene glycol-RGD hydrogel with tenascin.
Journal of tissue engineering and regenerative medicine - 1 Mar 2016
Naghdi Pejman, Tiraihi Taki, Ganji Fariba, Darabi Shehram, Taheri Taher, Kazemi Hadi
Abstract excerpt
Polyethylene glycol hydrogel (PEG) conjugated with arginyl glycyl aspartic acid (RGD) (PEG-RGD) has been considered to be a scaffold in three-dimensional (3D) culture that improves neurite outgrowth; on the other hand, tenascin C controls neural growth and differentiation. In this study, the effect of a combined RGD and tenascin C mixture in 3D culture (3D-PEG-RGD-TnC) on the survival, growth and differentiation...
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