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Article

Development of a Refined Tenocyte Differentiation Culture Technique for Tendon Tissue Engineering

8 Sept 2012

Abstract excerpt

We have established that human tenocytes can differentiate in the absence of exogenous fetal bovine serum (FBS) but in the presence of insulin-like growth factor-1 (IGF-1) and transforming growth factor-β3 (TGF-β3). The extent of tenocyte differentiation was assessed by examining cell survival, collagen synthesis, cell morphology and expression of tenocyte differentiation markers such as scleraxis (Scx),...

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PMID: 22964470
DOI: 10.1159/000341426

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