Article
Targeted mutation analysis of endometrial clear cell carcinoma.
Histopathology - 1 Apr 2015
Hoang Lien N, McConechy Melissa K, Meng Bo, McIntyre John B, Ewanowich Carol, Gilks Cyril Blake, Huntsman David G, Köbel Martin, Lee Cheng-Han
Abstract excerpt
AIMS: Endometrial clear cell carcinomas (CCC) constitute fewer than 5% of all carcinomas of the endometrium. Currently, little is known regarding the genetic basis of endometrial CCC. METHODS AND RESULTS: We performed genomic and immunohistochemical analyses on 14 rigorously reviewed pure endometrial CCC. The genomic analysis consisted of sequencing the coding regions of 26 genes implicated previously in...
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