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Is infection with hypermutable Pseudomonas aeruginosa clinically significant?

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 May 2015

Auerbach Adi, Kerem Eitan, Assous Marc Victor, Picard Elie, Bar-Meir Maskit

Abstract excerpt

BACKGROUND: Hypermutable Pseudomonas aeruginosa (HPA) with high mutation rate due to defects in the DNA mismatch repair genes are frequently isolated in the sputum of cystic fibrosis (CF) patients. These isolates tend to be multidrug resistant and may be better adapted to the CF lung environment....

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Identifiers

PMID: 25308183
DOI: 10.1016/j.jcf.2014.09.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25308183-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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