Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of IL-2 and IL-2R SNPs on proliferation and tumor- killing activity of lymphokine-activated killer cells from healthy chinese blood donors.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Li Yan, Meng Fan-Dong, Tian Xin, Sui Cheng-Guang, Liu Yun-Peng, Jiang You-Hong

Abstract excerpt

One of the goals of tumor immunotherapy is to generate immune cells with potent anti-tumor activity through in vitro techniques using peripheral blood collected from patients. However, cancer patients generally have poor immunological function. Thus using patient T cells, which have reduced in vitro proliferative capabilities and less tumor cell killing activity to generate lymphokine-activated killer (LAK)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Donors
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Healthy Volunteers

Share to Interleukin-2

Share to Killer Cells, Lymphokine-Activated

Share to Leukocytes, Mononuclear

Share to Receptors, Interleukin-2

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 25292096
DOI: 10.7314/apjcp.2014.15.18.7965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of IL-2 and IL-2R SNPs on proliferation and tumor- killing activity of lymphokine-activated killer cells from healthy chinese blood donors.PMID 25292096Read ↗

The association between -330T/G polymorphism of interleukin 2 gene and bladder cancer.Semantic proximity Read ↗

Association of Interleukin-2-330T/G and Interleukin-10-1082A/G Genetic Polymorphisms with B-Cell Non-Hodgkin Lymphoma in a Cohort of Egyptians.Semantic proximity Read ↗

Interleukin-2 gene polymorphisms and prognosis of breast cancer.Semantic proximity Read ↗

Interleukin 2 gene polymorphisms are associated with non-Hodgkin lymphoma.Semantic proximity Read ↗

Antitumor effect of large doses IL-2-activated HLA haploidentical peripheral blood stem cells on refractory metastatic solid tumor treatment.Semantic proximity Read ↗

Association of the interleukin-2 polymorphisms with interleukin-2 serum levels and risk of nasopharyngeal carcinoma.Semantic proximity Read ↗

Association of IL-2 polymorphisms and IL-2 serum levels with susceptibility to HBV-related hepatocellular carcinoma in a Chinese Zhuang population.Semantic proximity Read ↗

Identification of a novel CD56- lymphokine-activated killer cell precursor in cancer patients receiving recombinant interleukin 2.Semantic proximity Read ↗

High-producer interleukin-2 genotype increases risk for acute graft-versus-host disease after unrelated donor bone marrow transplantation.Semantic proximity Read ↗

Functional and phenotypic analyses of interleukin 2-activated tumor-infiltrating lymphocytes.Semantic proximity Read ↗

IL-2 -330 T/G SNP and serum values-potential new tumor markers in neuroendocrine tumors of the gastrointestinal tract and pancreas (GEP-NETs).Semantic proximity Read ↗

Human spleen and peripheral blood lymphocytes activated by interleukin-2 have similar phenotypic and functional characteristics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.