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Article

Analysis of polymorphisms in RIG-I-like receptor genes in German multiple sclerosis patients.

Journal of neuroimmunology - 15 Dec 2014

Varzari Alexander, Bruch Kathrin, Deyneko Igor V, Chan Andrew, Epplen Joerg T, Hoffjan Sabine

Abstract excerpt

Variation in genes encoding retinoid acid-inducible gene I (RIG-I)-like receptors (RLRs) has been implicated in the pathogenesis of autoimmune disorders. We investigated if polymorphisms in the IFIH1, RIG-I, LGP2 and VISA genes influence the risk for multiple sclerosis (MS) in a German case-control cohort comprising 716 patients and 706 controls. Evaluation of 18 single nucleotide polymorphisms (SNPs) in the four...

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Source

Identifiers

PMID: 25288302
DOI: 10.1016/j.jneuroim.2014.09.015

Genes

IFIH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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