Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Capping of vesicular stomatitis virus pre-mRNA is required for accurate selection of transcription stop-start sites and virus propagation.

Nucleic acids research - 29 Oct 2014

Ogino Tomoaki

Abstract excerpt

The multifunctional RNA-dependent RNA polymerase L protein of vesicular stomatitis virus catalyzes unconventional pre-mRNA capping via the covalent enzyme-pRNA intermediate formation, which requires the histidine-arginine (HR) motif in the polyribonucleotidyltransferase domain. Here, the effects of cap-defective mutations in the HR motif on transcription were analyzed using an in vitro reconstituted transcription...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Polyadenylation
Share to RNA Caps
Share to RNA-Dependent RNA Polymerase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RNA Precursors

Share to Terminator Regions, Genetic

Share to Transcription Initiation Site

Share to Viral Proteins

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 25274740
DOI: 10.1093/nar/gku901
PMCID: PMC4231761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Capping of vesicular stomatitis virus pre-mRNA is required for accurate selection of transcription stop-start sites and virus propagation.PMID 25274740Read ↗

GDP polyribonucleotidyltransferase domain of vesicular stomatitis virus polymerase regulates leader-promoter escape and polyadenylation-coupled termination during stop-start transcription.Semantic proximity Read ↗

Signature motifs of GDP polyribonucleotidyltransferase, a non-segmented negative strand RNA viral mRNA capping enzyme, domain in the L protein are required for covalent enzyme-pRNA intermediate formation.Semantic proximity Read ↗

Signatures of Host mRNA 5′ Terminus for Efficient Hantavirus Cap SnatchingSemantic proximity Read ↗

Viral RNA capping: Mechanisms and antiviral therapySemantic proximity Read ↗

Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirusSemantic proximity Read ↗

African Swine Fever Virus NP868R Capping Enzyme Promotes Reovirus Rescue during Reverse Genetics by Promoting Reovirus Protein Expression, Virion Assembly, and RNA Incorporation into Infectious VirionsSemantic proximity Read ↗

An unconventional pathway of mRNA cap formation by vesiculovirusesSemantic proximity Read ↗

Initiation, Elongation, and Realignment during Influenza Virus mRNA SynthesisSemantic proximity Read ↗

Mechanism of RNA synthesis initiation by the vesicular stomatitis virus polymeraseSemantic proximity Read ↗

Molecular architecture and diversity of StopGo/2A translational recodingSemantic proximity Read ↗

Storage of cellular 5′ mRNA caps in P bodies for viral cap-snatchingSemantic proximity Read ↗

An Engineered T7 RNA Polymerase for efficient co-transcriptional capping with reduced dsRNA byproducts in mRNA synthesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.