Article
The prognostic value of HPV status and p16 expression in patients with carcinoma of the anal canal.
PloS one - 1 Jan 2014
Roldán Urgoiti Gloria B, Gustafson Karla, Klimowicz Alexander C, Petrillo Stephanie K, Magliocco Anthony M, Doll Corinne M
Abstract excerpt
BACKGROUND: In anal cancer studies, the detection frequency of high-risk HPV (human papillomavirus) is variable, depending on the method used. There are limited data reporting results of different HPV detection techniques in the same clinical series, and very few correlating results with clinical outcome. OBJECTIVES: To evaluate tumor expression of p16/HPV16 using three different methods, and to determine their...
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