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Article

Targeted exon sequencing fails to identify rare coding variants with large effect in rheumatoid arthritis.

Arthritis research & therapy - 30 Sept 2014

Bang So-Young, Na Young-Ji, Kim Kwangwoo, Joo Young Bin, Park Youngho, Lee Jaemoon, Lee Sun-Young, Ansari Adnan A, Jung Junghee, Rhee Hwanseok, Lee Jong-Young, Han Bok-Ghee, Ahn Sung-Min, Won Sungho, Lee Hye-Soon, Bae Sang-Cheol

Abstract excerpt

INTRODUCTION: Although it has been suggested that rare coding variants could explain the substantial missing heritability, very few sequencing studies have been performed in rheumatoid arthritis (RA). We aimed to identify novel functional variants with rare to low frequency using targeted exon sequencing of RA in Korea. METHODS: We analyzed targeted exon sequencing data of 398 genes selected from a multifaceted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25267259
DOI: 10.1186/s13075-014-0447-7
PMCID: PMC4203956

Genes

VSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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