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Article

Role for the A domain of unprocessed accumulation-associated protein (Aap) in the attachment phase of the Staphylococcus epidermidis biofilm phenotype.

Journal of bacteriology - 1 Dec 2014

Conlon Brian P, Geoghegan Joan A, Waters Elaine M, McCarthy Hannah, Rowe Sarah E, Davies Julia R, Schaeffer Carolyn R, Foster Timothy J, Fey Paul D, O'Gara James P

Abstract excerpt

The polysaccharide intercellular adhesin or the cell wall-anchored accumulation-associated protein (Aap) mediates cellular accumulation during Staphylococcus epidermidis biofilm maturation. Mutation of sortase, which anchors up to 11 proteins (including Aap) to the cell wall, blocked biofilm development by the cerebrospinal fluid isolate CSF41498. Aap was implicated in this phenotype when Western blots and...

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Identifiers

PMID: 25266380
DOI: 10.1128/JB.01946-14
PMCID: PMC4248850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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