Article
A novel Staphylococcus aureus biofilm phenotype mediated by the fibronectin-binding proteins, FnBPA and FnBPB.
Journal of bacteriology - 1 Jun 2008
O'Neill Eoghan, Pozzi Clarissa, Houston Patrick, Humphreys Hilary, Robinson D Ashley, Loughman Anthony, Foster Timothy J, O'Gara James P
Abstract excerpt
Device-associated infections involving biofilm remain a persistent clinical problem. We recently reported that four methicillin-resistant Staphylococcus aureus (MRSA) strains formed biofilm independently of the icaADBC-encoded exopolysaccharide. Here, we report that MRSA biofilm development was promoted under mildly acidic growth conditions triggered by the addition of glucose to the growth medium. Loss of...
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