The metalloprotease S ep A governs processing of accumulation‐associated protein and shapes intercellular adhesive surface properties in S taphylococcus epidermidis

Abstract excerpt

The otherwise harmless skin inhabitant Staphylococcus epidermidis is a major cause of healthcare-associated medical device infections. The species' selective pathogenic potential depends on its production of surface adherent biofilms. The Cell wall-anchored protein Aap promotes biofilm formation in S. epidermidis, independently from the polysaccharide intercellular adhesin PIA. Aap requires proteolytic cleavage...

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