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Article

Role of Cytokine Signaling in Group B Streptococcus‐Stimulated Expression of Human Beta Defensin‐2 in Human Extraplacental Membranes

29 Sept 2014

Abstract excerpt

PROBLEM: Group B Streptococcus (GBS) is a leading cause of neonatal morbidity and mortality. We tested the hypothesis that the choriodecidua plays a role in GBS-stimulated human beta defensin(HBD)-2 increases in amnion cells through a secreted factor of choriodecidual origin. METHOD OF STUDY: Human amnion epithelial cells were treated with choriodecidual GBS-conditioned medium, live GBS, lipoteichoic acid (LTA),...

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Share to Infant Nutrition and Health
Share to Neonatal and Maternal Infections
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PMID: 25263616
DOI: 10.1111/aji.12325

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