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Article

Human trophoblast responses to Porphyromonas gingivalis infection

5 Jul 2010

Abstract excerpt

Porphyromonas gingivalis is a periodontal pathogen that is also associated with preterm low-birthweight delivery. We investigated the transcriptional responses of human extravillous trophoblasts (HTR-8) to infection with P. gingivalis. Over 2000 genes were differentially regulated in HTR-8 cells by P. gingivalis. In ontology analyses of regulated genes, overpopulated biological pathways included mitogen-activated...

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PMID: 20618699
DOI: 10.1111/j.2041-1014.2010.00573.x

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