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Article

Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia.

Clinical lymphoma, myeloma & leukemia - 1 Feb 2015

Quintás-Cardama Alfonso, Zhang Nianxiang, Qiu Yi Hua, Post Sean, Creighton Chad J, Cortes Jorge, Coombes Kevin R, Kornblau Steven M

Abstract excerpt

BACKGROUND: Tripartite motif (TRIM)-62 is a putative tumor suppressor gene whose role in leukemia is unknown. MATERIALS AND METHODS: We evaluated the effect of TRIM62 protein expression in patients with acute myeloid leukemia (AML). We used reverse-phase protein array methodology to determine TRIM62 levels in leukemia-enriched protein samples from 511 patients newly diagnosed with AML. RESULTS: TRIM62 levels in...

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Share to Endoplasmic Reticulum Chaperone BiP
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25248926
DOI: 10.1016/j.clml.2014.07.011
PMCID: PMC4560255

Genes

TRIM62
FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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