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Article

CircNFIX knockdown inhibited AML tumorigenicity by the miR-876-3p/TRIM31 axis

12 Sept 2022

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) is one of the most common malignant myeloid diseases in adults with a dismal prognosis. We aimed to explore the effects of circNFIX on the proliferation and apoptosis of AML cells. METHODS: The expressions of circNFIX, miR-876-3p and tripartite motif (TRIM) 31 in the bone marrow specimens of AML patients and AML cell lines were detected by qRT-PCR or western blot. Cell...

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PMID: 36094501
DOI: 10.1080/16078454.2022.2115699

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