Potassium inwardly-rectifying channel subfamily J member 11 (KCNJ11) gene polymorphism in Egyptian type 2 diabetic patients: a single-center study.

doi:10.1007/s11033-024-10035-4

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Potassium inwardly-rectifying channel subfamily J member 11 (KCNJ11) gene polymorphism in Egyptian type 2 diabetic patients: a single-center study.

Molecular biology reports - 7 Nov 2024

Abdelazem Abdallah S, Gaber Osama Abdelaziz, Hussein Samia, Nasr Fatma Mahmoud Elsaid, M Elshorbagy Eman A, Ibrahim Sara Mohammed, Abdel-Hameed Abdullah Mohammad, Rashad Mai Hamdy, El-Shal Amal S, Abdelnabi Al-Shabrawy M

Abstract excerpt

BACKGROUND: The KCNJ11 gene belongs to the potassium channel gene family. It has a major role in the secretion of insulin. Genetic variations in KCNJ11 are possibly responsible for the progression of type 2 diabetes mellitus (T2DM). In this study, we investigated the possible correlation between KCNJ11 (rs5210) gene polymorphism and T2DM. SUBJECTS AND METHOD: This study included 92 individuals divided into two...

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PMID: 39508922
DOI: 10.1007/s11033-024-10035-4

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