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Article

BMP15 c.-9C>G promoter sequence variant may contribute to the cause of non-syndromic premature ovarian failure.

Reproductive biomedicine online - 1 Nov 2014

Fonseca Dora Janeth, Ortega-Recalde Oscar, Esteban-Perez Clara, Moreno-Ortiz Harold, Patiño Liliana Catherine, Bermúdez Olga María, Ortiz Angela María, Restrepo Carlos M, Lucena Elkin, Laissue Paul

Abstract excerpt

BMP15 has drawn particular attention in the pathophysiology of reproduction, as its mutations in mammalian species have been related to different reproductive phenotypes. In humans, BMP15 coding regions have been sequenced in large panels of women with premature ovarian failure (POF), but only some mutations have been definitely validated as causing the phenotype. A functional association between the BMP15...

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Identifiers

PMID: 25246117
DOI: 10.1016/j.rbmo.2014.07.018

Genes

BMP15
PITX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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