Article
Premature ovarian failure and gene polymorphisms.
Current opinion in obstetrics & gynecology - 1 Aug 2009
van Dooren Marieke F, Bertoli-Avellab Aida M, Oldenburg Rogier A
Abstract excerpt
PURPOSE OF REVIEW: Premature ovarian insufficiency (POI) is a common disorder affecting approximately 1% of women under the age of 40 years. Until now, research aiming to identify genetic causes of POI was mostly based on candidate gene approaches. Recently, several genes have been identified using this approach, and genome-wide searches were conducted. In this review, we discuss these studies and propose future...
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