Article
Oral lichen planus and intake of drugs metabolized by polymorphic cytochrome P450 enzymes.
Oral diseases - 1 Jul 2003
Kragelund C, Thomsen C E, Bardow A, Pedersen A M, Nauntofte B, Reibel J, Torpet L A
Abstract excerpt
OBJECTIVE: To study if patients with oral lichen planus (OLP) had a medication profile different from that of a control group without oral mucosal lesions. It was hypothesized that OLP lesions might result from poor drug metabolism (PM) because of genetic variation of the major cytochrome P450-enzymes (CYPs with a PM-risk). SUBJECTS AND METHODS: Dental records of 172 OLP patients were reviewed in this...
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