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Article

Genetic features of late onset primary hemophagocytic lymphohistiocytosis in adolescence or adulthood.

PloS one - 1 Jan 2014

Wang Yini, Wang Zhao, Zhang Jia, Wei Qing, Tang Ran, Qi Junyuan, Li Lihong, Ye Liping, Wang Jijun, Ye Ling

Abstract excerpt

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of uncontrolled immune activation leading to extreme inflammation. Primary HLH was once believed to be a disease that occurred only in infancy or young children, and was rarely diagnosed in adults. It is now understood that patients can develop primary HLH in their adolescence or adulthood. This study included 252 adolescent and adult...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25233452
DOI: 10.1371/journal.pone.0107386
PMCID: PMC4169386

Genes

PRF1
STX11
STXBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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