Article
Mutagenic effects of ionizing radiation on immature rat oocytes.
Radiation research - 1 Oct 2014
Asakawa Jun-ichi, Kamiguchi Yujiroh, Kamiya Kenji, Nakamura Nori
Abstract excerpt
Estimates of genetic risks from radiation delivered to humans are derived largely from mouse studies. In males, the target is spermatogonia and a large amount of information is available. In contrast, in females, immature oocytes are the target, but extrapolations from mice to humans are not very definitive because immature mouse oocytes are highly sensitive to radiation and die by apoptosis, which is not the...
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