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Article

Protection of a single dose west nile virus recombinant subviral particle vaccine against lineage 1 or 2 strains and analysis of the cross-reactivity with Usutu virus.

PloS one - 1 Jan 2014

Merino-Ramos Teresa, Blázquez Ana-Belén, Escribano-Romero Estela, Cañas-Arranz Rodrigo, Sobrino Francisco, Saiz Juan-Carlos, Martín-Acebes Miguel A

Abstract excerpt

West Nile virus (WNV) is a neurovirulent mosquito-borne flavivirus. High WNV virulence was mainly associated with lineage 1 strains, but recent outbreaks have unveiled circulation of highly virulent lineage 2 strains. Co-expression of flavivirus prM and E glycoproteins drives the assembly of recombinant subviral particles (RSPs) that share antigenic features with virions. Mouse immunization with lineage 1 WNV...

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Identifiers

PMID: 25229345
DOI: 10.1371/journal.pone.0108056
PMCID: PMC4168257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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