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Article

N-linked glycans on influenza A H3N2 hemagglutinin constrain binding of host antibodies, but shielding is limited.

Glycobiology - 1 Jan 2015

Pentiah Kevin, Lees William D, Moss David S, Shepherd Adrian J

Abstract excerpt

The extent of the role of N-linked glycans (N-glycans) in shielding influenza A hemagglutinin (HA) against host antibodies has proved controversial, with different authors making widely different assumptions. One common assumption is that N-glycans physically shield surface residues that are near to glycosylation sites, thereby preventing antibodies from binding to them. However, it is unclear, from existing...

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Share to Amino Acid Motifs
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25227423
DOI: 10.1093/glycob/cwu097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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