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Stem cell senescence. Effects of REAC technology on telomerase-independent and telomerase-dependent pathways

16 Sept 2014

Abstract excerpt

Decline in the gene expression of senescence repressor Bmi1, and telomerase, together with telomere shortening, underlay senescence of stem cells cultured for multiple passages. Here, we investigated whether the impairment of senescence preventing mechanisms can be efficiently counteracted by exposure of human adipose-derived stem cells to radio electric asymmetrically conveyed fields by an innovative technology,...

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PMID: 25224681
DOI: 10.1038/srep06373

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