Article
ERG positive prostatic cancer may show a more angiogenetic phenotype.
Pathology, research and practice - 1 Dec 2014
Strzępek Aleksandra, Kaczmarczyk Karolina, Białas Magdalena, Szpor Joanna, Dyduch Grzegorz, Szopiński Tomasz, Chłosta Piotr, Okoń Krzysztof
Abstract excerpt
In Western populations, roughly half of prostatic carcinoma (PC) cases show translocations involving the ETS transcription factor family genes and overexpression of the ERG transcription factor. ETS transcription factor family is known to be involved in angiogenesis. Microvascular density (MVD) influences the prognosis of various solid tumors, yet its significance in PC remains unclear. The aim of the study was...
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