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Article

Simultaneous assessment of aneuploidy, polymorphisms, and mitochondrial DNA content in human polar bodies and embryos with the use of a novel microarray platform.

Fertility and sterility - 1 Nov 2014

Konstantinidis Michalis, Alfarawati Samer, Hurd Douglas, Paolucci Marta, Shovelton John, Fragouli Elpida, Wells Dagan

Abstract excerpt

OBJECTIVE: To develop a microarray platform that allows simultaneous assessment of aneuploidy and quantification of mitochondrial DNA (mtDNA) in human polar bodies and embryos. DESIGN: Optimization and validation applied to cell lines and clinical samples (polar bodies, blastomeres, and trophectoderm biopsies). SETTING: University research laboratory and a preimplantation genetic diagnosis (PGD) reference...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25217868
DOI: 10.1016/j.fertnstert.2014.07.1233

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PGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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