Article
Immunomodulatory role of high-density lipoproteins: impact on immunosenescence.
Age (Dordrecht, Netherlands) - 1 Jan 2014
Larbi Anis, Fortin Carl, Dupuis Gilles, Berrougui Hicham, Khalil Abdelouahed, Fulop Tamas
Abstract excerpt
Natural aging is accompanied by a dysregulation of the host immune response that has well-known clinical consequences but poorly defined underlying causes. It has previously been reported that advancing age is associated with an increase in membrane cholesterol level in T cells. The aim of this study was to investigate whether high-density lipoprotein (HDL) can modulate the age-related accumulation of membrane...
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