Article
Identification of genetic markers for treatment success in heart failure patients: insight from cardiac resynchronization therapy.
Circulation. Cardiovascular genetics - 1 Dec 2014
Schmitz Boris, De Maria Renata, Gatsios Dimitris, Chrysanthakopoulou Theodora, Landolina Maurizio, Gasparini Maurizio, Campolo Jonica, Parolini Marina, Sanzo Antonio, Galimberti Paola, Bianchi Michele, Lenders Malte, Brand Eva, Parodi Oberdan, Lunati Maurizio, Brand Stefan-Martin
Abstract excerpt
BACKGROUND: Cardiac resynchronization therapy (CRT) can improve ventricular size, shape, and mass and reduce mitral regurgitation by reverse remodeling of the failing ventricle. About 30% of patients do not respond to this therapy for unknown reasons. In this study, we aimed at the identification and classification of CRT responder by the use of genetic variants and clinical parameters. METHODS AND RESULTS: Of...
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